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The team have started looking, but could find no clear pattern except that one form of nicotine-induced acetylation, that of H3 histones (histones come in five varieties), could be blocked by a molecule called RGZ.
Protons first slide into the channel, where they are bound by a molecule called retinal.
One pathway is triggered by a molecule called vascular endothelial growth factor (VEGF).
One step in the metabolism of beverage alcohol (i.e., ethanol) in the liver is the oxidation of ethanol by a molecule called cytochrome P450 2E1 (CYP450).
The normal apoptosis response in the squid, which happens early in the colonization of the light organ, is triggered by a molecule called 'lipid A' (Foster et al., 2000).
When the T-cell antigen receptor (TCR) recognizes antigen in the context of the antigen-presenting cell's Class II MHC, simultaneous engagement of CD28 by a molecule called B6 on the antigen-presenting cell delivers the "second signal" that activates the T-cell.
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In 2009, Agios researchers discovered that the mutated enzyme leaves a different by-product, a molecule called 2-hydroxyglutarate, or 2-HG, which appears to switch off certain genes in the cell nucleus.
They could reliably select for this phenotype because S. rosetta can be made to form rosette-like colonies in the laboratory by adding a molecule, called a sulfunolipid, which is produced by a bacterial species (Alegado et al., 2012).
By creating a molecule called an artificial transcription factor in the laboratory, he hopes to switch off the production of the toxic mutant Huntingtin protein.
Apparently by secreting a molecule called vascular endothelial growth factor (VEGF), shown previously to help guide blood vessel development.
PARIS--As scientists race to finish a rough draft of the human genome, a European consortium is about to launch an effort to pinpoint every key spot in our genetic code where cells turn genes on and off by adding a molecule called a methyl group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com