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In the N2 domain of the gene-3-protein of phage fd, two consecutive β-strands are connected by a mobile loop of seven residues (157 163).
Here, we show, by X-ray crystallography and mutagenesis, that OGT adopts the (metal-independent) GT-B fold and binds a UDP-GlcNAc analogue at the bottom of a highly conserved putative peptide-binding groove, covered by a mobile loop.
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The integrin inhibitory profile of disintegrins primarily depends on the sequence of a tripeptide located at the apex of a mobile loop and constrained in its active conformation by the appropriate pairing of disulfide bonds.
This internal flexibility is suggested also by the proteolysis experiments where the presence of a proteolytic cleavage site between D1 and D2 indicates that a mobile loop connects the two domains.
Some of the apical domain hydrophobic groups now exposed on the GroEL surface are bound by the seven mobile loops of the GroES cochaperone.
In HbpA, helix α11 forms one side of a hydrophobic channel, the opening of which also includes the mobile loop 195 203, as revealed by the apo structure.
When bound to GroEL, the disordered cochaperone mobile loops become structurally ordered, although physical interaction with GroEL occurs only through a universally conserved tripeptide in the mobile loop (Landry et al. 1993, 1996; Xu et al. 1997).
From a bioinformatics approach, we have identified hydrophobic regions on the non-substrate protein sequences by using an online server, known as SIM alignment tool, in which we got patches similar to that of mobile loop of GroES.
This paper presents an approach to creating a semantic map of an indoor environment incrementally and in closed loop, based on a series of 3D point clouds captured by a mobile robot using an RGB-D camera.
For non-iPhone users, the app can be accessed by a mobile site: www.tsa.gov/mobile.
The two compartments were separated by a mobile guillotine door.
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