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Next, mapper intermediate outputs are collected by a master controller and grouped by their key values.
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AMPK and other signals are then integrated by mTOR, a master controller of metabolism, growth, and redox potential 39. Activation of AMPK accompanied by a decline in phosphorylation of two mTOR substrates (p70S6K and 4E-BP1) confirms that these regulators were perturbed following treatment.
The other controller in the cascade is a master controller that adjusts the set point of the slave controller.
An example is shown in Fig. 1, where a chain of ten nodes attached to a master controller is depicted.
We asked what if this universal controller could become a master controller to take over any drone that was in your airspace?
Therefore, Spo0A is considered as a "master controller" for solvent production in C. acetobutylicum[ 72].
PGC-1β is a master controller of hepatic energy homeostasis in part through regulation of mitochondrial oxidative metabolism genes.
BRCA1 serves as a "master controller" of HR, binding and regulating many downstream affectors including Mre11-Rad50-NBS1 (MRN) complex [ 14].
PPARgamma was shown to have a key role in adipogenesis and proposed to be a master controller of the "thrifty gene response" leading to efficient energy storage.
Cell-culture experiments on isolated monocytes demonstrated that resistin regulates proinflammatory cytokine secretion through the nuclear factor-κB pathway (22), a master controller of the proinflammatory process.
40, 41 CREB-regulated PGC-1 α is a master controller of mitochondrial biogenesis and antioxidant proteins associated with maintaining mitochondrial membrane integrity.
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