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Are you prepared to leave a black hole in every service station across the country, only for it to be replaced by a Marks & Spencer selling average sandwiches and their creepy own brand crisps?
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Jupiter was by a sign marked "Moose Crossing".
Depletion of ATP was accompanied by a marked reduction of plasmalemmal phosphatidylinositol 4,5-bisphosphate (PIP(2)) content.
The former lasted until 1944, when it was replaced by a Mark 27 microwave radar though it was supplemented by a Mark 3 main armament fire control radar.
This reduced bacillary load was also accompanied by a marked reduction in the pulmonary, splenic and hepatic pathology.
This later effect was demonstrated by a marked reduction of cellular Bid protein expression.
Successful inhibition of mTORC1 by rapamycin was evidenced by a marked reduction of S6K1 phosphorylation (Supplementary Fig S2A).
Endotoxin shock is characterized by a marked oxidant stress [ 26] and a rapid production of different cytokines [ 27].
Even the normal pregnancy is characterized by a marked reduction in maternal insulin sensitivity in the second and third trimesters.
Knockdown of Smad7 was accompanied by a marked reduction of CDC25A protein expression while CDC25B and CDC25C levels remain unchanged.
Autopolyploidization did indeed induce cytological changes, as manifested by a marked reduction in the frequency of normal tetrad formation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com