Paul Kalanithi was, and, through his memoir, he still is: "While all doctors treat diseases, neurosurgeons work in the crucible of identity: every operation on the brain is, by necessity, a manipulation of the substance of our selves.... the question is not simply whether to live or die, but what kind of life is worth living".
In the present, tactile version of the contextual-cueing paradigm, by contrast, a manipulation of set size was not possible; instead, this was fixed at four items, comprising one target and three distractors on each trial.
They presented a method for isolating the relative impact of each one of these single processes by means of a manipulation of the sequence of trials.
This formulation is based on the assembly of the smoothed dynamic stiffnesses of each component in a classical way, followed by a manipulation in terms of structural paths to provide the smoothed frequency responses of the whole structure.
A control structure is proposed, where the main element is temperature control of pre-fractionator side, achieved by a combined manipulation of the side reboiler external duty and recompressed vapour by-pass.
These items were followed by a manipulation check, consisting of four items.
Was Coco Chanel really "infuriated" by a "needless manipulation of hemlines"?
Many actions can be controlled by a simple manipulation of valves.
He found that he could radically distort the developmental phases of his insect subjects by a selective manipulation of their hormonal levels.
Having obtained their wealth by buying state assets on the cheap, trading heavily on their Kremlin connections, most of Russia's "oligarchs" survived the devastating financial crash of August 1998 by a cynical manipulation of their remaining properties.
