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It is known that the rate of lipolysis in EAT is increased compared to other fat depots such as popliteal or perirenal [5], which might be in part mediated by a low expression of ADRA2A.
A cellular counterpart that provides TCR/CD3 signals without CD28 engagement is represented by immature DC, characterized by a low expression of surface MHC II molecules and low to absent levels of costimulation by CD80/CD86.
This effect could be explained in part by a low expression of proapoptotic genes.
Measles virus in SSPE is characterized by a low expression of viral envelope proteins as a result of mutational events.
The down-regulation of the glycogen metabolism was also indicated by a low expression value of PYGL.
APL cells are further characterized by a low expression of P-glycoprotein (P-170), probably responsible for the particularly high sensitivity to anthracyclines [ 56, 57].
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LNCaP cells were characterised by IL-FABP and a low expression of E-FABP mRNA.
For HULC, we grouped by median expression into a low expression and a high expression group with an 11.87 cut-off.
For H19, HULC, and UCA1, we grouped by median expression into a low expression and a high expression group with cut-offs of 9.28, 11.87, and 6.51, respectively.
The other four genes (PCNA, NET-1, Bcl-2 and Bax) and MVD groups, both the middle and lower groups, were also treated the same by combining them into a low expression group and low MVD group ; whereas the group was an overexpression group and higher MVD group.
No Flv1 protein, however, was detected by immunoblotting, most probably due to a low expression level of flv1 (see Materials and Methods).
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