The analytical performance of cTnT N-MIP performed by differential pulse voltammetry showed a linear range from 0.01 to 0.1 ng mL−1 (r=0.995, p«0.01), with a very low limit of detection (0.006 ng mL−1).
Under the optimized experimental conditions, the model target protein of thrombin was highly sensitively detected by the proposed aptasensing system in a linear range of 0.067 32.4 nM with a detection limit of 0.03 nM (approximately 90 amol target molecules).
Given the combined electrochemical activity of PARS and excellent conductivity of BMIMBF4, the PARS/BMIMBF4/GCE has been successfully used for catechol determination by differential pulse voltammetry (DPV) with a linear range of 0.10 to 500 μM.
Also, the sensitivity of some of the previously reported assays is not great, for example, an HPLC UV method published by Farthing et al. had a linear range for the detection of IOT in plasma from 10 to 50 µg/mL [40].
Conventional immunohistochemistry using antibodies for active, phosphorylated Akt has been suggested, but this approach is limited by its low linear range and by the difficulty in introducing a second stain for normalizing purposes.
The ascorbic acid sensor fabricated by this film showed a large linear range for the detection of ascorbic acid between 1.0 × 10−6 and 1 × 10−2 M with a high sensitivity of 182 mA M−1 cM−1.
The proposed biosensor could be used to detect glucose based on the consumption of O2 with the oxidation of glucose catalyzed by GOx and exhibited a wide linear range of glucose from 0.05 mM to 4.5 mM and low detection limit of 10 μM.
But the spatial resolution is limited by the linear range of the random walk of the positron, which is a mean of 0.2 mm (maximum 2.4 mm) in the case of F. However, lower spatial resolution can be compensated by a higher FDG uptake (hot spot phenomena) so that smaller neoplasms will be detected if their SUVmax is large enough to be differentiated from the background noise (Figs. 1, 2, 3).
According to the manufacturer, the minimum detection limit of the assay was 7.8 pg/mL as defined by the linear range of standard curves.
In this model, we preprocess the data by linear range transformation.
