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We consider the case of two identical cells coupled by a gap junction.
Moreover, individual branches of different cells can be connected by gap junctions with a coupling parameter R GJ. Fig. 1 a A network of two cells connected by a gap junction (GJ).
If the branches of two cells are coupled by a gap junction, the location of this coupling can be treated as a special node point on an extended branching structure.
Fig. 2 A network of two identical cells, each consists of an infinite dendritic cable, coupled by a gap junction Fig. 3 All trips (including the shortest trip for G ˆ m − ( x, y, ω ) shown by a dashed arrow) and the corresponding coefficients A trip at the GJ for two identical cells.
It has previously been shown in Langendorff-perfused whole hearts that arrhythmic tendencies arising during acidification can be reduced by a gap junction opener (Eloff et al. 2003), indicating that during acidosis reduced conduction velocity may generate an arrhythmic substrate separate from the reduced ΔAPD90.
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Our results suggest that PAR6 could be used as a potential marker of germ cells for the primordial follicle formation, and the expression of PAR6 by a gap junction-dependent process may contribute to the formation of primordial follicles and the maintenance of oocytes at the diplotene stage.
A role for astrocytic gap junctional communication in metabolite spreading in vivo was tested by first microinfusing a gap junction inhibitor, α-glycyrrhetinic acid or oleamide, into inferior colliculus of non-stimulated, conscious rats, then infusing labelled glucose (Cruz et al., 2007).
Tumor growth was significantly delayed by treatment with either a gap junction inhibitor or TMZ, the standard chemotherapeutic treatment for GBM.
The aim of this study was to investigate the role of gap junctions in atrial fibrillation (AF) by analysing the effects of a gap junction enhancer and blocker on AF vulnerability and electrophysiological properties of isolated hearts.
A gap junction controlled by the parameter R GJ and located at x = 0 divides two dendrites into four semi-infinite segments: m −, m +, n −, and n +.
During the first postnatal days, the synchronized oscillatory activity of the mouse cerebral cortex is driven by subplate activity and spreads through a gap junction-coupled neuronal network (Dupont et al. 2006).
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