Sentence examples for by a functional polymorphism from inspiring English sources
Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction.
2) Do MCP-1 levels in T1D patients differ according to sex, age, duration of diabetes, metabolic control as measured by hemoglobin A1c and the presence of different diabetic complications? 3) Are serum MCP-1 levels genetically determined by a functional polymorphism in the MCP-1 promoter region?
Caspi et al. (2002) found the adverse effect of maltreatment on antisocial behaviors to be moderated by a functional polymorphism in the monoamine oxidase A (MAOA) gene.
In addition, studies in human adolescents have found an association between testosterone level and increasing white matter that is modulated by a functional polymorphism in the androgen receptor gene, the short arm polymorphism of which leads to more efficient androgen signalling than the long arm polymorphism.
It is markedly inhibited by lead (30), and a functional polymorphism in ALAD might modulate the adverse effects of lead burden on phobic anxiety symptoms (31).
Thus, a functional polymorphism in one gene may be compensated for by a functionally similar or downstream gene.
Zhao BY, Lu JG, Yin JK, Liu HQ, Guo X, Yang YF, Ge NJ, Zhu Y, Zhang HX, Xing JL. (2012) A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma.
A functional polymorphism of COMT, Val108/158 Met, affects prefrontal function, and the high-activity Val allele has been reported to be a genetic risk factor for schizophrenia.
Moreover, unlike many polymorphisms, the ACTN3 R577X polymorphism is a functional polymorphism, with the XX genotype resulting in complete loss of function.
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition.
Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.
