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This argument was strengthened by a functional analysis, which is described later in this section.
The structural and biochemical data are complemented by a functional analysis that demonstrates how RecX actively promotes RecA dissociation from established filaments.
These results were further associated with ERBB2 gene amplification status and then corroborated by a functional analysis using small interfering RNA (siRNA) transfected in a mammary cancer cell line.
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Therefore, we aimed to identify genes involved in the positive and negative regulation of acetic acid-induced PCD by optimizing a functional analysis of a yeast Euroscarf knock-out mutant collection.
Recently, the proteomic profile of metabolic proteins in the invasive glioblastoma phenotype has been studied by applying a functional analysis using the Ingenuity Pathway Knowledge Base (Ingenuity Systems, Redwood City, CA) [ 39].
To gain a better insight on the biological processes, cellular components and molecular functions that are affected by the differentially expressed genes, we performed a functional analysis by using the DAVID toolbox (see Methods) [ 35, 36].
We then performed a functional analysis by flow cytometry using standard methods and which maximized the data we could obtain from cultured cells.
We therefore performed a functional analysis by in vitro mutagenesis in E. coli to investigate whether the MGMT I143V or I143V/K178R variants could have an effect on MGMT activity.
Amino acids that are differentially conserved between T2R and V1R receptors, e.g. YT2R/CV1R in EC1, and C..YT2R/S..QV1R in TM3, may be expected to be relevant for the functional differences between T2R and V1R receptors, and would be plausible candidates for a functional analysis by site-directed mutagenesis in future studies.
Using a functional analysis provided by the Engagement system of the Appraisal theory, this paper aims to uncover some of the ways in which the teacher makes use of the verbal and visual resources in children's picture books to promote engagement with the texts.
To estimate the changes in expression patterns caused by hypermethylation of 5' CGIs, we performed a functional analysis of gene expression data obtained from cDNA microarray experiments.
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