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QUESTION FROM DAVID: He seems to recycle is lines hopes it gets better for him NICK PAUMGARTEN: Math, common sense undermined by a double negative.
The wholly elusive grail of land art! Instantly iconic, it was transformed into legend by a double negative: the disappearance of the jetty, a mere two years after it was created, followed a year later by the premature death of its creator, Robert Smithson.
Deployment of the gene-regulatory network (GRN) responsible for skeletogenesis in the embryo of the sea urchin Strongylocentrotus purpuratus is restricted to the large micromere lineage by a double negative regulatory gate.
Rac and Rho are coupled by a double negative feedback loop [ 15- 18].
ZEB1 is known to be regulated by a double negative feed forward loop involving the miRNA 200 family 30, 41.
The potential gain in cost-effectiveness from the expense of the extra test is the longer interval of safety supported by a double negative result.
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Such an autocatalytic activation system that is coupled to PTP activity, by for example a double negative feedback, offers robustness against biological noise and conveys external stimuli into threshold-activated responses (Grecco et al., 2011).
Consistent with the repression of let-7 by c-Myc, increased expression of c-Myc in Burkitt lymphoma cells is associated with decreased let-7 expression [ 69]. c-myc is also targeted by let-7, suggesting a double negative feed-back loop in which c-Myc represses let-7 transcription and let-7 in turn represses c-Myc (Fig. 3) [ 69].
- She creates a double negative by crossing out the terms "not baked" and "not fried".
"No editor will print a double negative," Mr. Taub declares by way of illustration.
However, it has been shown that ZEB1 triggers a double negative feedforward loop, by downregulating its own inhibitors (i.e., the mir-200 family members) [ 47, 48].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com