Sentence examples for by a direct physical from inspiring English sources

These investigators suggest that Ena normally inhibits kinesin-mediated transport by a direct physical association.

However, the membrane association of CD97 was preserved and only disappeared in cells with a totally disorganized cytoskeleton (fig. 5c) suggesting that CD97 is not likely to couple to F-actin by a direct physical interaction.

We immunoprecipitated Flag-tagged BAP55 from transfected S2 cells and observed an interaction between Flag-BAP55 and Akirin-V5 (Supplementary Fig S2D), suggesting that the recruitment of the Brahma complex onto Akirin-dependent promoters is not triggered by a direct physical interaction with Relish.

In addition, absence of lamin A/C is associated with 1) alterations in the nuclear transcription required for osteoblastogenesis and; 2) abnormal interaction between Runx2 and MAN-1, a protein of the nuclear envelope that is closely regulated by lamin A/C through a direct physical interaction [14].

"State Farm policies cover additional living expenses for people who are displaced by damage, what we call a direct physical loss," said Holly Anderson, a State Farm spokeswoman.

Furthermore, a direct physical interaction was observed by co-migration of purified HHARI and NEDD8-CUL1 RBX1 using size-exclusion chromatography.

A number of models for how distal regulatory elements communicate with their target promoters have been suggested and the simplest model with the most supporting evidence is of a direct physical interaction brought about by chromatin looping.

Compared to their desorption-followed by-adsorption route, direct physical contact of RAC with PCBs bound to WHS exhibited negligible contribution to the availability of PCBs for dechlorination reaction.

Based on these facts, we propose that the inhibition of the PKCε activity, and hence the suppression of the SMMC-7721 hepatoma cell growth, was achieved though the formation of a complex by direct physical interaction between C/EBPβ 3'UTR RNA, PKCε and CK18.

We propose that the Cterm acts as a chaperone by direct physical contact with the mutated mt-tRNA in vivo, helping it to maintain the conformation suitable to proficiently interact with its cognate aminoacyl-tRNA synthetase or other molecular partners.

There is now a general consensus that the interaction between Patched1 and Smoothened is mediated by a small molecule (or molecules) that is regulated by Patched1, rather than by direct physical interactions between the two (Taipale et al., 2002).