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Finally, based on the recently resolved hCB1 receptor crystal structure, we propose that the differences in RT can be explained by a different binding mode of antagonist 9 from short RT antagonists that is able to displace unfavorable water molecules.
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Molecular modeling studies by docking suggested a different binding mode for the most active derivatives, when compared to natural hit chalepin.
The P. berghei-GFP adhesion to CSA and HA indicates that iRBC could co-express ligands for different receptors, represented either by separate adhesive molecules or by different binding sites on a single molecule.
In 14-3-3 14-3-3 14-3-3ding groove in a strucommon dimeric protein can bindinged by multiple, distinct sequences provided by many different bindingrooveners.
Noticeably, the ratio of bound to unbound AID was variable to some extent (see, for example, Figure 1A vs. Figure 1B); these differences in binding efficiency of AID to beads may be explained by technical variation between experiments, and by different binding capacity of the various beads.
Instead, we obtained informative DNA duplex stability prior by assuming different binding preferences for different TFs.
This is explained by the different binding strengths, swelling behaviour in the electrolyte, electrode porosities, and possible 'buffer' effects of the compact and the finely distributed binders.
Three types of mortars (concrete) are designed in order to simulate the Hagia Sophia historic mortar, by using different binding material: lime/metakaolin, hydraulic lime, lime/cement.
This discrepancy can be explained by the different binding sites of the used antibodies.
The apparently contradictory evidence might be explained by the different binding properties of plasminogen kringle domains to PrP in varying detergent conditions.
These results also suggest that the observed differences between the groups were not caused by different binding capacities to the GAD65Ab epitope defined by b96.11.
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