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These clinical trials suggest that PPSV23 is not highly effective against nonbacteremic pneumococcal pneumonia, but do not rule out the possibility that the vaccine may lead to a reduction in risk of pneumococcal pneumonia that is not reflected by a detectable difference in risk of all-cause pneumonia evaluated in these trials.
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The 0.2% difference in protein content between Zhongzheyou 1 and Guodao 6 would be too low to result in a detectable difference in roughness by the trained panel (Champagne et al. 2009).
In other industries, however, there was not a detectable difference in job or payroll growth between the winning and losing counties.
One of these (Marker-5) produced a detectable difference between XX, XY, and YY individuals.
In a new paper in the Proceedings of the National Academy of Sciences, they report a detectable difference between the genes of sea stars before the epidemic and the survivors.
Our sample size was determined by considerations of both a minimum detectable difference between groups and logistical constraints associated with enrolling and testing participants.
This translates to a minimum detectable difference between reviews of 0.64 'AMSTAR points'.
Based on the agreement results of rater A the smallest detectable difference (SDD) for an individual level was calculated for each movement by multiplying the SD of the differences by 1.96: 1.96* SD change.
An analysis of the levels of endogenous HGF secretion in S3DN cells by ELISA revealed no detectable difference between the WT, NEO4 and S3DN cell lines (data not shown).
Instead of reflecting on what would be the smallest important difference (or the largest unimportant difference), investigators may be tempted to engage themselves in the "sample size samba" [ 2], by retrofitting the expected detectable difference to the available number of participants.
Let us execute the suggested adjustment of δ for reliability, by assuming that the 'smallest detectable difference' (SDD) [ 7] is a meaningful difference between subjects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com