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Chondrogenesis is driven by a coordinated effect of hormones (such as parathyroid hormone (PTH)), morphogens (such as Hedgehog (Hg) or wingless (Wnt) proteins) and cytokines (such as members of the bone morphogenetic protein (BMP) and transforming growth factor (TGF -β family) through their respective receptors [ 5].
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The dynamics of both SAG1 and BAG1 transcript levels suggested a coordinated effect of perturbation of gene expression.
However, many disease phenotypes are determined not by individual genes, but by the coordinated effect of many genes.
Why must you train your brain and neural network to produce a particular coordinated effect or action?
The decreased activity of TH2-CP by Zn2+ may be due to the coordinated effect of the hydroxide ion (ZnOH+) on the catalytic zinc ions (Larsen and Auld 1989).
Similar coupling between regulation of transcription and mRNA capping carried out by other factors could potentially explain the coordinated effect we observed for genes that were repressed upon Myc activation.
We hypothesised that multiple sites would therefore explain a coordinated regulatory effect on the expression of BLK.
Full functionality of tumor-conditioned murine MDSCs requires the coordinated effect of both IL-13 and IFNα, released by the cells in an autocrine fashion, and results in the dual expression of arginase and nitric oxide synthase II.
To cleanly separate the unilateral and the coordinated effect of market shares on prices, we first center the market shares toward a zero mean by subtracting the HHI.
The octahedral coordination of Ti1 is completed by a coordinated isopropyl alcohol.
The homeostatic drive underlying these systemic effects is similarly evident at the cellular level, where hypoxia is met by a coordinated transcriptional response that seeks to minimise hypoxic injury and redress the oxygen debt.
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