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In this study, the active site of the 3TC-resistant (M184V) RT is constructed by a computational method, which clearly shows that the side chain of Val184 occupies the binding site for the nucleoside triphosphates.
A manually identified position that was overlooked by a computational method was called a false negative.
Let P and B denote the sets of complexes predicted by a computational method and real ones in the benchmark, respectively.
The cumulative sum (CUSUM) method was applied to local hospital data for outbreak detection by calculating the numbers of daily patient visits and identifying those that were above an outbreak threshold (set by a computational method described below).
The solutions were characterised by both sensory descriptive analysis and by a computational method by which the frequency of the observed Notch concentration levels were recorded at each parameter value.
Microinversions were also identified by a computational method that combined the multiple sequence alignments with the results of complementary strand alignments for all pairs of sequences (Additional file 2, Figure S1).
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A conserved motif (MTCM1) was identified in the 5'-flanking regions of T. thermophila MTT1, MTT3 and MTT5 genes and the T. pyriformis homolog, TpMT-1, by using a computational method free of preconceptions.
We conclude by showing a computational method which combines the result of Propositions 4.1 and 5.2.
For analysis of a possible linkage among C677T (rs1801133), A1298C (rs1801131) and other polymorphisms (rs2066470, rs2066462, rs1994798), haplotypes of the five variations in Korean population (N = 192) were built by employing a computational method (EM algorithm).
Therefore, assisting humans by means of a computational method that can continuously identify and aid in resolving inconsistencies adds significant value.
Up-regulation of p53 target genes in FHL2−/− cells was evidenced by Gene Set Enrichment Analysis (GSEA), a computational method for assessing enrichment of a predefined gene list in one class compared with another [37].
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by a design method
by a graphical method
by a stochastic method
by a photometric method
by a radioactive method
by a sequential method
by a computational cost
by a computational docking
by a direct method
by a computational experimentation
by a computational exploration
by a computational vortex
by a computational platform
by a computational comparison
by a cold method
by a controversial method
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