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It is therefore subject to a tight regulation achieved by a complex protein network [1].
The regulation of the mitochondria intrinsic pathway is performed by a complex protein network in which the B-cell lymphoma protein-2 (Bcl-2) family members form a central checkpoint that determines whether a cell lives or dies [20].
In even the simplest modern systems, such as RNA viruses with the replication fidelity of only ~10-3, replisation is catalyzed by a complex protein replicase [ 10].
Cytokinesis is driven by a complex protein machinery, termed divisome that is recruited upon assembly of FtsZ, a bacterial tubulin homologue, at the site of the future division.
MicroRNAs (miRNAs) are a class of short, single stranded, approximately 18 25 nucleotide noncoding RNAs and are cleaved from 70 to 100 nucleotide hairpin precursors by a complex protein system that involves the ribonucleases (RNases) III Drosha and Dicer, Pol-II-dependent transcription, and members of the argonaute family [ 6, 7].
In even the simplest modern systems, such as RNA viruses with the replication fidelity of only ~10-3, replisation is catalyzed by a complex protein replicase; even disregarding accessory subunits present in most replicases, the main catalytic subunit is a protein that consists of at least 300 amino acids [ 20].
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The material properties of our own bodies are governed largely by the extracellular matrix, a complex protein and carbohydrate network that gives shape to tissues and organs.
CO is a complex protein produced by a collaboration between the mitochondria and the nucleus.
This process is carried out by a highly complex protein machinery called the divisome, which is currently thought to encompass approximately 18 proteins of which many are conserved among different bacteria [1], [2], [3], [4].
Lck activity is finely tuned by a complex of proteins comprising plasma membrane-embedded protein tyrosine phosphatase CD45 and cytoplasmic protein tyrosine kinase Csk bound to scaffold protein PAG (CBP), and to adaptor protein TSAD [ 45, 46].
Meiotic recombination is initiated by double-strand DNA breaks (DSBs) induced by a complex of proteins including the conserved Spo11 protein (Rec12 in fission yeast).
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