Sentence examples for by a combinatorial modification from inspiring English sources

By a combinatorial modification of four key residues within the coenzyme binding sites, different GAPDH mutants with varied coenzyme specificity were constructed.

This complexity in histone modifications might not only be seen as a simple code, but rather as an ingenious chromatin 'language' where different biological outcomes are defined by the combinatorial modification of basic building blocks [13].

Each combinatorial modification is observed in a single histone tail by tandem mass spectrometry.

The strength of this association is often modulated by a combinatorial array of post-translational histone tail modifications, including acetylation, methylation, ubiquitination and phosphorylation [ 10- 12].

DNA and histone modification maps obtained from numerous genome-wide chromatin immunoprecipitations studies and the identification of histone codes by MS demonstrate that DNA and histone modifications form combinatorial modification patterns within chromatin.

Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational methods capable of joint analysis of multiple maps to reveal combinatorial modification patterns.

The essence of language is words and syntax, each generated by a combinatorial system in the brain.

Many functional categories are specifically influenced by a combinatorial effect.

The silkworm OBPs could play a chemosensory role in chemoreception by a combinatorial interaction with chemoreceptors.

The findings of Borde et al (2009) emphasize the importance of histone modifications in facilitating DSB formation and open doors into an exploration of the complex and combinatorial modifications that function in this process.

These data enabled the design of combinatorial modifications that almost completely offset 3-HP toxicity in minimal medium resulting in a 20 g/L and 25-fold increase in tolerance and specific growth, respectively.