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Raman spectroscopy of the polymer surface confirmed that dedoping was the dominant process which was accompanied by a clear reduction of the emeraldine salt form of the coating to the leucoemeraldine base form within the defect.
Although exposure to SRI-286 (10 in Figure 2) was also accompanied by a clear reduction in the synthesis of α- and keto-mycolates, this effect was less dramatic than after exposure to TAC or in SRI-224 (data not shown), consistent with the higher MIC value of SRI-286 against M. bovis BCG strain Pasteur (MIC99 = 10 25 µg/ml for SRI-286, 0.25 µg/ml for SRI-224, 0.5 µg/ml for TAC, [6]).
The bariatric procedure LSG was followed by a clear reduction of the Firmicutes/Bacteroidetes ratio.
Such an enhanced expression was accompanied in Chinese cabbage by a clear reduction in malondialdehyde content, an indicator of unsaturated lipid degradation by ROS (Sun et al. 2010).
In knockout models for these factors, the more clearly linked to a severe abnormality of placentation is the αV- β3 integrin knockout mouse; αV- β3 integrin deficiency is associated with a 50% reduction in litter size and fetal mortality of 10% and is accompanied by a clear reduction in placental perfusion [ 35].
We previously studied the effects of 2 weeks of perioperative doxycycline treatment on vascular inflammation in AAA, and found that doxycycline has a profound but selective effect on vascular inflammation, as indicated by a clear reduction in aortic wall IL-6 and IL-8 levels, and a respective 75%and96%6% reduction in aortic wall neutrophil and cytotoxic T-cell content.
Similar(54)
Trimebutine maleate, another prokinetic drug, when associated to a proton pump inhibitor may improve gastric motility in patients with gastric ulcer by inducing a clear reduction in periods of tachygastria and bradygastria periods but with no effects on GE [ 85].
This result was supported by RT qPCR experiments showing a clear reduction in XBP1s mRNA expression (Fig 2E).
We observed that activin increased Smad2 linker region phosphorylation and that this phosphorylation was dependent on p38 activity, because inhibition by SB203580 led to a clear reduction in linker region phosphorylation.
The expression of cIRF7 but not of cIRF7(C508A) resulted in cleavage by the HCV protease, and a clear reduction of viral protein and RNA syntheses in both replicon and HCVcc-infected cells (Figs. 6A and 6B).
A clear reduction by a factor of 0.76 (on average, SD = 0.24, N = 8) in the ratio was observed for PT compared to PP.
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