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This side effect was caused by a cellular inflammatory reaction, attributed to a T helper cell type 1 response to epitopes located in the central and C-terminal part of Aβ(1 42) [12], [12].
For example, damage to the bladder following SCI is characterized by a cellular inflammatory response, accompanied by decreased functional integrity of the uroepithelium due to a loss of tight junction proteins; this pathology persists for several months after SCI [10].
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The direct recognition of bacteria by Nod2 likely triggers a cellular inflammatory response to breech of host defences by potential pathogens.
Accumulating evidence supports that binding of ligands to RAGE results in a cellular inflammatory response by activation of the transcription factor NF- κB and subsequent stimulation of NF- κB-regulated cytokines release.
Introduction of rCARDS toxin to the airways of mice or baboons resulted in a cellular inflammatory response characterized by a dose-dependent early vacuolization and cytotoxicity of the bronchiolar epithelium followed by a robust peribronchial and perivascular lymphocytic infiltration.
It is a rare vasculitis characterized by a highly cellular inflammatory thrombus with relative sparing of the vessel wall and can be distinguished from other types of vasculitis based on the rarity of systemic signs and symptoms and the absence of both elevated acute-phase reactants and immunological markers.
Another important element affecting aging is thought to be cumulative damage to macromolecules by reactive oxygen and nitrogen species (ROS/RNS) induced by unbalanced cellular inflammatory responses, or generated via mitochondrial dysfunction (Berlett and Stadtman, 1997; Dizdaroglu et al., 2002).
MSU crystals are surrounded by a cellular corona of inflammatory and resident macrophages, including multinucleated giant cells that have features of osteoclasts.
These changes were accompanied by cellular inflammatory infiltrates, where lymphocytes were the prominent inflammatory cells present in the late phase, while granulocytes were prominent in the early phase.
Mice treated with bleomycin display subpleural scarring characterized by cellular inflammatory cell infiltration and extracellular matrix deposition in the alveoli, as has been described in clinical cases of idiopathic pulmonary fibrosis [ 2, 3].
During stimulation, MPO is secreted by these cells and activates cellular inflammatory signaling cascades [29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com