Sentence examples for by a cellular component from inspiring English sources
There is increasing evidence for the "cancer stem cell (CSC) hypothesis", which holds that cancers are driven by a cellular component that has stem cell properties, including self-renewal, tumorigenicity and multi-lineage differentiation capacity.
The cancer stem cell hypothesis proposed that tumors are driven by a cellular component that retains stem cell properties, including self-renewal, tumorigenicity, and multilineage differentiation capacity [ 11, 12].
Multiple studies have demonstrated that invasion and metastasis are mediated by a cellular component that displays high ALDH1 activity [ 27, 78], suggesting that ALDH1A1 can be a significant target for cancer therapy.
Epitope tagging is a powerful approach used to enable investigations of a cellular component by elucidating its localization, interaction partners, and/or activity targets.
These findings suggest that protection was at least partially mediated by a cellular immune component and that the induction of Th2 and immunoregulatory cytokines by a KIN1148-adjuvanted vaccine may be particularly beneficial for ameliorating the immunopathogenesis that is associated with influenza viruses.
In MM, microenvironment is represented by the cellular component of a normal bone marrow together with extracellular matrix proteins, adhesion molecules, cytokines, and growth factors produced by both stromal cells and PC themselves.
Among these six proteins, three belong to the subunits of NuA4 in baker's yeast, within an essential histone H4/H2A acetyltransferase complex annotated by GO cellular component term GO 0032777 [ 35, 36].
Therefore, we propose for protein complex prediction algorithms a preprocessing step where the input PPI network is segregated by informative cellular component GO terms.
The 310 differentially expressed proteins were categorized by their cellular component and biological function using Gene Ontology analysis (GO) or DAVID functional annotation.
This was further supported by GO cellular component overrepresentation test results.
The networks are first segregated by informative cellular component GO terms before these algorithms are run.
