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Messenger RNAs are decorated by a cap structure, which is essential for their translation into proteins.
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The proportion of transcripts with a cap structure is increased by elevating c-Myc expression, resulting in increased rates of translation.
These mRNAs are transcribed by a discontinuous transcription mechanism; they acquire a 5' cap structure and become 3' polyadenylated, which makes them equivalent to host cellular mRNAs [ 12].
Although sg-mRNA contains a cap structure, cleavage of eIF4G by poliovirus (PV) 2Apro or HIV-1 PR does not impair its translation [14].
We also compared reporters with or without a cap structure.
It lacks a 5' cap structure but contains a highly structured 5' untranslated region (UTR) [42].
The effect of A-cap structure is modeled by making the cap-dependent initiation step very slow (by making the k1 parameter very small).
The 5′-end of the ssRNA genome is decorated by a RNA cap structure (N7meGpppA2′Ome-RNA).
These struggling United States teams hurt the Canadian teams both directly by diluting the share of Canadian teams in the league, and indirectly by compelling a salary cap structure that is meant to protect the struggling American teams (but which has yet to make most of them profitable).
Translation efficiency is positively regulated by the 5' cap structure and the 3' poly(A) tail.
Specifically, we saw that translation initiation driven solely by the cap structure or solely by the poly(A) tail was partially responsive to miCXCR4, while only an mRNA carrying both end modifications was subject to the full extent of translational repression [19].
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