Here's how it works: Companies need to submit a brief application by April 27 that summarizes what makes their product groundbreaking and buzzworthy.
A brief application summary is presented in Table 1.
The primer may be set off by the brief application of heat (from a burning fuse or an electrically heated wire), by friction, or by mechanical shock (like the impact of the firing pin of a gun).
A small volume of fluorescently-tagged Aβ1 42 was ejected into the slice by the brief application of pressure (10 50 ms, 20 30 psi).
See related research by Kredel et al., A recent study [ 1], conducted in an animal model of acute lung injury, compared a ventilation strategy in which lungs were inflated by brief application of 50 cmH2O pressure followed by increased positive end-expiratory pressure (recruitment strategy) versus conventional ventilation.
It can be clearly seen that the amplitude and duration of the Ca2+ spike induced by the brief application of CCh in Ca2+-free solution, in the presence of CPA, were increased.
However, our findings on the inhibitory effect (i.e., channel suppression) of PKG on Kir6.2/SUR2A channels in inside-out patches (Fig. 2) seem to be in contradiction to those reported by Han et al. [26], in which a positive effect (i.e., channel activation) was induced by brief application of PKG to sarcKATP channels in inside-out patches excised from native cardiomyocytes.
Contractions were evoked by a brief (4 min) application of muscarinic agonist, carbachol, or by electrical field stimulation (EFS; ref. 29) from a constant-current source, with a train of pulses for 4 s (frequency 8 Hz, pulse width 0.1 ms for selective nerve stimulation, or pulse width 1 ms for direct muscle stimulation); trains were applied every 90 s.
