Sentence examples for by SNPs in coding from inspiring English sources

SNPs in coding regions are one of the most important DNA variants for quantitative trait locus (QTL) mapping, because some Mendelian and genetically complex traits are caused by SNPs in coding regions [ 16].

The patterns of nucleotide polymorphism were analyzed by targeting SNPs contained in coding sequences of FLICs.

Evidence of positive selection for each gene was calculated by taking Sn4 SNPs identified in coding regions and measuring dN/dS using the CNFGTR model (Yap et al. 2010) as implemented in PyCogent 1.5.1 (Knight et al. 2007).

This wide range of coverage makes it advantageous to discover unlinked common SNPs in coding and non-coding regions by screening one or only a few animals.

However, because only a small fraction of SNPs are in coding regions that results in only an estimated 2 to 20% fraction of GWAS associations driven by non-synonymous SNPs.

The amplified products were sequenced using an ABI3730 sequencer by BGI.> The localization of SNPs in coding regions was based on annotation of gene models as provided by the Brassica Genome Database (http://www.ocri-genomics.org/bolbase/).org/bolbase/

To identify potential causal ENU mutations, SNPs were filtered as previously described, with additional filtering being applied to identify SNPs in splice sites (within 10 bps of an exon) or non-synonymous SNPs in coding regions, and by zygosity.

100 SNPs were chosen at random to estimate the overall percentage of SNPs in coding regions.

In our results, we observed that structural effects caused by SNPs in 5′- or 3′-UTR are similar to those caused by SNPs in protein coding region (fig. 3 D).

Gene Ontology (GO) term enrichment analyses were performed independently on transcripts significantly over- or under transcribed or affected by differential SNPs in their coding region (Additional file 9: Figure S4).

Go term enrichment analyses were conducted on i) transcripts significantly over transcribed in insecticide-selected strains compared to the susceptible strain, ii) transcripts significantly under transcribed in insecticide-selected strains compared to the susceptible strain and iii) transcripts affected by differential SNPs in their coding sequence as compared to the susceptible strain.