BW-based scaling, however, could be completely misleading, when R is indeed large.
The effect of BW using the allometric scale on clearance and Ep endogenous production improved the model and partly explained the between-subject variability [ 13].
At baseline and after half a year (t = 32 weeks) the body weights (without coats, shoes etc). of all patients' were recorded on a decimal scale (TANITA BW-800, 'Frederiksberg Vægtfabrik', Copenhagen, Denmark).
While allometric scaling with BW to an exponent of 0.75 or BSA represent appropriate approaches for the achievement of comparable exposures across a wide age range for many drugs, BSA-based dosing would not be appropriate for carboplatin due to its reliance on renal clearance and the disproportionally low GFR observed in infants.
We found a strong correlation between BW, measured with the standard scale, and mAseff values based on CT dose modulation.
However, the braking force (7.5% BW) used in this large scale longitudinal study was probably adjusted to the young children but not to the most powerful adolescents whose performances were possibly underestimated.
BW was measured using a digital scale on days 21 and 28 of age.
BW was determined using an electronic scale while patients were wearing only underwear.
Body weight (BW) was determined using a portable scale (Seca®, model 770, Germany) with a precision of 0.1 kg.
Low tidal volume (Vt) is protective, but Vt is scaled to body weight (BW) and may be high in functionally small ARDS lungs.
He already owns the No. 2 in the German market, Unitymedia Kabel BW, and is a big believer in scale.
