Exact(1)
Ebselen is part of the National Institutes of Health Clinical Collection, a chemical library of bioavailable drugs considered clinically safe but without proven use [ 24].
Similar(57)
Several recent clinical trials targeting β-amyloid (A β) pathology in Alzheimer's disease (AD) have shown evidence of reducing the accumulation of A β plaques, but without proving a slowing of cognitive decline.
NSR – normal of serum reference UNSR – Upper normal serum reference Clinical details of the individuals without proven LM but with CSF kappa/lambda FLC ratios outside the serum reference range (4/12) were as follows: Patient 12 (CSF kappa/lambda ratio of 4 (Table 2) had an intracerebral manifestation of a post-transplantation lymphoproliferative disorder.
Of interest, we found the beneficial renal effects of AP to be similar in patients with or without proven Gram-negative infections, but this does not exclude endotoxin detoxification being an important mechanism by which AP protects the kidneys.
However, in critically ill patients with and without proven intestinal ischemia serum D-lactate levels were equally elevated but the combined group proven and likely ischemia had a significantly higher D-lactate.
Often controversial and difficult to asses, this type of programme is out place on the federal level and has little chance of gaining wide acceptance without proven success.
While Carroll was seen as having undoubted potential, it seemed a huge price to pay for someone without proven pedigree at the top level.
Four patients (5%) received curative antibiotics (more than 24 h) without proven pneumonia diagnosis and without respiratory sample during the first 48 h.
These drugs are considered as 'endocrine manipulations without proven OS benefit'.
These disorders are mainly described in case studies, without proven incidence rates.
Use of either protocol was without proven safety or efficacy in Ebola virus infected humans.
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