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Two markers on GBSSII (GBSSII-F and GBSSII-IF) were identified association with GL in five environments but with small effects.
Other genomic regions associated with VL and WG were identified also but with small effects.
The right interval behaves oppositely, but with small effects; HET increases COs in HOM: HOM/HOM 5cM; HET/HOM 6cM; HOM reduces COs in HET: HOM/HET 4cM; HET/HET 5cM.
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Those discharged to rehabilitation demonstrated significantly higher means with regard to age, HLOS, intensive care unit length of stay (ICULOS), days on mechanical ventilator, and probability of death (P < 0.001), but with small effect sizes.
Populations with this type of demographic history have been useful for identifying rare recessive alleles, but common variants with small effects have still been difficult to find.
Future linkage studies may benefit in power from denser marker panels [54] and larger sample sizes, but detection of loci with small effects and gene identification require other methods [55].
GWA is considered to be more powerful than linkage analysis for detecting the effects of common alleles with small effects but is less powerful when traits have a complex genetic determination, including epistasis.
The Pareto principle assumes a small but non-zero effect for the SNP with small effects, whereas the original BayesB of [ 2] assumed no effect for such SNP.
These patterns also generally held for the second step, messaging, but with smaller effects.
In these data we observed the same pattern that we found in the group data, but with smaller effects.
This enabled them to 'quantitative trait loci' (QTLs), with small effects on susceptibility to soft scald.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com