Sentence examples for but when bound to from inspiring English sources

When bound to GDP, RABs are inactive, but when bound to GTP, they become activated and interact with several effector proteins (Ung et al. 2013), including SNAREs, during the tethering of cargo at post-Golgi compartments (Cai et al. 2007).

There are seven E. coli sigma factors, which have no enzymatic activity, but when bound to core RNAP provide the ability for the newly formed holoenzyme to recognize a unique set of gene promoters and initiate transcription [18], [19].

SNRNP200 activity is stimulated by GTP-loaded EFTUD2, but when bound to GDP, EFTUD2 represses SNRNP200 activity 9, 10.

The same pattern held for CDK2 which complexes with several different cyclins, but when bound to cyclin E pushes the cell from G1 to S phase (G1/S transition).

The protein CBFβ lacks a DNA-binding domain, but when bound to Runx, it increases the DNA-binding affinity of the RD several fold, substantially enhancing its transcriptional activity (reviewed in [ 32]).

Thus, the F ab' 2, when present as a soluble molecule, but not when bound to T cells, might lose some functional activity as a consequence of partial reduction to F ab').

The enzyme's function is reduced but not eliminated when bound to the inhibitor.

The fluorescence of the triphenylmethylene MG dye is quenched when free in solution but dramatically increases when bound to the aptamer.

The conserved N-terminal domain contains an ATP-binding pocket with a lid that is open during ADP binding but is closed when bound to ATP.

Here, we describe the synthesis and biological evaluation of 22S-hexyl analog 5 (22S-Hex), wasch was designed to be a stronger VDR antagonist than 4. Unexpectedly, 5 showed partial agonistic but not antagonistic activity when bound to VDR, indicating that it is not necessarily true that the bulkier the side chain is, the stronger the antagonistic activity will be.

Plaques may be non-toxic, but could become toxic when bound to metal ions [ 93 ].