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Grade 1 and 2 infusion related toxicities were relatively common during the first rituximab infusion but were uncommon with subsequent infusions.
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Solicited systemic reactions were uncommon, with mild to moderate headache being the most frequently observed event.
Mild hypoglycemic episodes were uncommon with EQW, although risk of hypoglycemia increased in combination with sulfonylureas.
Surgical complications were uncommon with a conversion rate of 0.6% and no mortality.
Adjudicated GI, CV/cerebrovascular and liver events were uncommon with all three treatments.
Adverse effects were uncommon with single doses of rofecoxib 50 mg, and rates of particular adverse effects were low.
Adverse events were uncommon, with less than 1% of subjects in each group experiencing endophthalmitis, intraocular inflammation, or cerebrovascular events.
Methicillin-resistant S. aureus occurred with similar frequency in the groups with health care-associated infection (52%) and nosocomial infection (61%) but was uncommon in the group with community-acquired bloodstream infection (14%) (P = 0.001).
Reported issues with RCA include metabolic alkalosis and acidosis, hyper- and hyponatremia and hypocalcemia, but these complications are uncommon with an accurate monitoring of the procedure [ 12, 16].
The vacuum extractor was associated with an increase in neonatal cephalhaemotomas and retinal haemorrhages, but serious neonatal injury was uncommon with either instrument and Apgar scores at 1 and 5 min were comparable [LOE: 1+].
Periprosthetic fractures after total ankle arthroplasty are uncommon, with most cases occurring intraoperatively.
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