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It is unclear whether the unlabelled hair follicle melanocytes are derived from SCPs as well but were not efficiently labelled by tamoxifen, or whether they are derived from dorsolaterally migrating cells.
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CphE was active when expressed heterologously in E. coli Mach1 pBluescriptSK- cphE al but was not efficiently pBluescriptSK- cphEtem.
One of the problems was that electrons in the terahertz lasers were not efficiently recycled and pumped back up.
The S418A and T557A mutants were not efficiently phosphorylated (Fig. 2E).
These findings strongly support the hypothesis that aggregate-prone proteins, such as α-synuclein, initially interact with p62, and then aggregation of the protein complex occurs in a p62-dependent manner but the aggregates are not efficiently degraded by autophagy.
This result is consistent with previous studies [ 24] and demonstrates that IDU present with advanced HIV disease not because they are tested for HIV infrequently, but rather because they are not efficiently linked to care.
Under higher injection current, it can be seen that heat is not efficiently dissipated, but accumulates in the area around the device instead.
The latter case would suggest that some toxic damage is not efficiently repairable but can instead be 'automatically' segregated by a passive, diffusion-based mechanism.
Therefore, there is either an exceedingly large number of pre-miRNAs in these datasets or, more plausibly, most of these candidates are not efficiently transcribed but could otherwise be recognized as miRNA precursors.
Several retinal cell-specific Cre lines have being made available, but most of them are not inducible or use promoters that are not efficiently expressed in adults.
We've shown here that in both people and mice, self-specific T cells are not efficiently removed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com