The protein has 5′-triphosphatase and diphosphatase activity for short RNAs but is less active toward mononucleotide triphosphates, suggesting its primary function in vivo is to dephosphorylate RNA 5′-ends.
Almost all tested compounds have remarkable activities against these three fungal strains, but are less active than nystatin (Table 5).
168 also showed strong activity against Gram positive bacteria, especially against MRSA, but was less active compared to compounds 169 and 171 [49].
At doses less than, or equivalent to, the LD10, isophosphoramide mustard retained high activity against cyclophosphamide-resistant L1210 and P388 leukaemias, but was less active against intracerebrally-implanted P388 leukaemia while cyclophosphamide produced a 4 log10 tumour cell reduction.
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The obtained results of testing antimicrobial activities of 3-aryl-4-formylsydnone N- 2,3,4,6-tetra-O-β-d-glucopyranosyl thiosemicarbazones 4a–o shows that some substaN- 2,3,4,6-tetra-O-β-d-glucopyranosyl thiosemicarbazonesare less active thaN- 2,3,4,6-tetra-O-β-d-glucopyranosyl thiosemicarbazones
Results in Tables 1 and 2 showed that immobilization through covalent adsorption led to more enzyme bound to Ag and Au nanoparticles, but is less active, than in the case of spacer-linked enzyme.
Frenatin 2.1S and 2.2S show potent bactericidal activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MIC ≤16 μM) but are less active against a range of Gram-negative bacteria.
The female assists in building, but is less active than the male.
