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Strong but variable expression of hK14 was present in the lungs of several independent lines of TG animals, comparable with the level seen in the positive control of normal human bronchial epithelial cells BEAS-2B.
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However, for PBMC cultured in SFM containing IFN-γ (or IL-12, data not shown), the few fibrocytes observed retained CD172a expression, but had variable expression of CD206 and CD209 (Figure 13).
One possible explanation for the observed variability in ciliopathy phenotypes may be the variable expression of conserved proteins or variability in the function of calcium binding proteins.
Finally, non-genetic factors may also play a role in the variable expression of HSCR, but have been hardly explored (Fu et al., 2010) because the specific contribution of such modifiers in congenital malformation is challenging to study in humans and even in mouse models.
The results obtained showed that OOCs expressed cytokeratin 10 and showed variable expression of cytokeratins 13 and 14.
Following culture procedure including electroporation, the produced cells showed mature DC morphology and phenotype characterised by no or very low proportion of CD14, but high expression of CD86 and HLA-DR with variable expression of CD83 (Table 2).
Although the mRNA of MUC2 was expressed at constant levels in PAC120 and HID tumours, a variable expression of the MUC2 protein was observed.
Interestingly, both tumors showed variable expression of basal/myoepithelial markers.
Variable expression of miRs has been associated with diverse vascular diseases [8 11].
Assaying esophageal SCC lines revealed variable expression of claudin-7, with some lacking expression completely.
CD14+ dermal dendritic cells (DDC) show variable expression of CD1a, CD1c, and CD163 (Haniffa et al., 2009).
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