In addition to unequal expression of X-linked genes, the small number of expressed genes present on the Y chromosome (and therefore only expressed in males) may be involved.
In fact, preliminary immunohistochemistry data of human acido-peptic mucosa demonstrate an unequal expression of asparagine synthetase throughout the gastric epithelium, with a clear localisation at the base of the glands up to the level of mucous neck cells (Supplementary Fig. S3).
One consequence of polyploidization is unequal expression of homoeologous loci.
Unequal expression of these alleles is termed allelic imbalance (AI).
Allelic imbalance, or unequal expression of allelic transcripts, could provide evidence of this.
Unequal expression of the alleles of autosomal genes is common in the human genome [ 1, 2].
Regulatory polymorphisms in cis-acting elements result in the unequal expression of alleles.
Plant responses to allopolyploidy include unequal expression of duplicated genes and gene silencing.
Allele specific expression (ASE) refers to unequal expression of multiple alleles of a gene in a given organism.
We found a hitherto unknown mutation-dependent unequal expression of mutant to wild-type MYH7-mRNA, which is paralleled by similar unequal expression of β-MHC at the protein level.
