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Genes for CDTa and CDTb could be variable due to some point mutations but this variability has not been studied as extensively as for TcdA and TcdB toxinotypes.
The number of small mutations was generally more variable (7% in Africa to 22% in Oceania) but this variability is likely explained by the fact that not all countries routinely assay for point mutations and other small lesions and indeed numbers of patients were significantly smaller, for example, in Africa compared to Europe (Fig. 4).
Here we focus on insect outbreaks and present evidence that a population of the willow leaf beetle Phratora vulgatissima (Coleoptera: Chrysomelidae) consists of individuals that vary with respect to oviposition rate, but this variability is enhanced at higher temperatures.
Consistent with predictions, the average speed of lever pressing initially varied greatly, but this variability decreased as the animals learned the task.
Blood glucose variability appears to correlate with mortality, but this variability may be an indicator of disease severity, rather than an independent predictor of mortality.
But, this variability is constant with time, and so we think that it does not incorporate any problem in order to detect if the system is in an epidemic phase.
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Significant between service variability in recovery rates was observed but predictors of this variability were also not investigated.
It is unclear why this variability occurs but differences between the power of the horns, deterioration of horns and the compatibility between seed and substrate could contribute to interassay differences.
CYP2C19 polymorphism plays an important role in this variability, but heritability estimates suggest that additional genetic variants remain unidentified.
Potentially the roles of stress and context may explain some of this variability, but examining the question in flies where there are relatively robust and standardized conditions to assess both is an opportunity to shed light on how sleep deprivation might affect aggression and the mechanisms that underlie the linkage.
Metastatic colorectal cancers (mCRCs) are clinically heterogeneous, but the genomic basis of this variability remains poorly understood.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com