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Both T1D and T2D are characterized by hyperglycemia, but the underlying pathogenic mechanisms are different.
Like other plant pathogenic Bipolaris species, it causes corn leaf spot, but the underlying pathogenic mechanism is totally unclear.
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The precise aetiology of systemic sclerosis (SSc) remains elusive, but significant advances over the past few years have improved our understanding of the underlying pathogenic processes and identified key pathways and mediators that are potential therapeutic targets.
Dysfunction of cortico-striato-thalamo-cortical circuitry is implicated in OCD, although the underlying pathogenic mechanisms are unknown.
It is widely believed that MS is an immune-mediated disease whose clinical manifestations and course, as well as response to therapy appear to be heterogeneous, as may be the underlying pathogenic mechanisms [1].
The second basis for biomarker research is the identification of proteins representing the host-specific response to a damaging agent usually performed as proteomic approach and better applicable in those cases where the underlying pathogenic agent is not to be anticipated.
PVD has been previously described by Flammer et al. to be the underlying pathogenic process in NTG [ 10, 73].
The identification and functional characterization of these myelomagenic mutations is necessary to better understand the underlying pathogenic mechanisms in this disease.
To identify potential therapeutic targets for these debilitating genetic skeletal disorders, current research is focused on understanding the underlying pathogenic mechanisms.
The underlying pathogenic processes of neurodegenerative disorders are similar and are linked to pathways that are important during the aging process.
However, in the last decade, monoclonal antibodies (mAbs) leading to immune-modulation of the underlying pathogenic process in RA, started a therapeutic revolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com