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After adjustment, ancestry remained significantly associated with lung function, but the large effect of adjustment for confounding among males (but not females) does not allow us to exclude the possibility that residual confounding may still account for these findings.
Recent meta-analysis on PPV predicted a mortality benefit of approximately 16% RRR in severe ARDS patients with a PaO2/FiO2 ratio of less than 100, but the large effect size of more than 50% RRR in the PROSEVA (Proning Severe ARDS Patients) trial has not been reported with any critical care intervention questioning the biologic plausibility of such a huge benefit [ 13].
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Most of these results were conditional effects, involving the tracking locus (with a large single-locus effect) and a tracked locus (with no main effect, but tracked by the large effect in the other locus).
Mr. Bloomberg has focused on the bartenders who will live longer because they no longer inhale regurgitated tobacco, but the larger effect of putting bars and restaurants off limits to smokers is indirect: serious numbers of active smokers quit -- and children never start -- because of the public disapproval these laws broadcast.
"Windows 7 will have some positive effects on overall PC demand, but the larger effect will come from the older base," Felice said.
A total of 974 genes were DE when testing for the effect of treatment using all patients, but the largest effect (1,058 DE genes) was observed in the TNF-positive group of patients.
Our study was powered to detect effect sizes of 0.22 in the MAI, but the largest effect size seen was 0.21 for minimal vs. control at 90 days, and this was in the wrong direction (minimal having a higher value).
Adapting contact patterns to mitigate a specific disease risk was as important as biosecurity measures for some farm types, but the largest effect was seen when combining biosecurity measures with more planned contact patterns.
In exploring the particular psychosocial health problems that constitute this syndemic, we found that each was associated with suicide related ideation and behavior, but the largest effect was found in evaluating the cumulative number of problems as predicted by syndemic theory.
43 A cost-effectiveness analysis reported that 'individually adapted behaviour change' and 'social support' programmes are the least cost effective but produce the largest effect, adding 35 43% increases in recommended physical activity.
Thinning and broadcast burning reduced canopy fuels in all forest types for several decades, but had the largest effect in forests with abundant fir.
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