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These results are consistent with previous findings that motor impairment in and of itself does not reduce health-related quality of life but the functional consequences of poor motor function including loss of self-care capabilities, inability to ambulate and loss of independence and its emotional consequences that may provide the link between physical impairment and low HRQoL [ 16, 35].
The brains of large mammals have lower rates of metabolism than those of small mammals, but the functional consequences of this scaling are not well understood.
In schizophrenia, GAD67 downregulation occurs in multiple interneuronal subpopulations, including the cannabinoid receptor type 1 positive (CNR1 +) cells, but the functional consequences of these disturbances are not well understood.
Like CPK, TRPM6 and TRPM7 undergo autophosphorylation [18], [28], [29] but the functional consequences for catalytic activity are unknown.
One likely explanation is that CB4 is recognized by TLRs other than TLR3 but the functional consequences of this interaction are not critical for survival.
Growth factor expression varied with the tumor transplantation site, but the functional consequences of these changes are unknown.
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Fullerene nanoparticles have been reported to specifically bind to and elicit persistent activation of hippocampal Ca2+/calmodulin-dependent protein kinase II (CaMKII), a multimeric intracellular serine/threonine kinase central to Ca2+ signal transduction and critical for synaptic plasticity, but the functional consequence of that modulation is unknown.
Previous work showed that dysferlin recruits PARVB to the sarcolemma.[42] PARVB can directly interact with integrin linked kinase, and is important for stabilizing focal adhesions.[52], [53] In the absence of dysferlin PARVB does not localize to the sarcolemma, but the functional consequence of this is unknown.[42] Calpain 3 is also in complex with dysferlin.
CK1α phosphorylates Ser45 but the functional consequence of this phosphorylation is not well understood.
More than 1000 SNPs have been identified in ESR1, but the functional consequence of each SNP has not been characterised.
Several serine/threonine kinases, such as PKA, GSK3, CK1 and DYRK2, can directly phosphorylate Gli2, but the functional consequence of these phosphorylations is connected to processing and degradation of Gli2 [48,49].
More suggestions(17)
but the practical consequences
but the functional impact
but the functional molecules
but the indirect consequences
but the functional disabilities
but the functional alterations
but the functional roles
but the political consequences
but the functional SNPs
but the economic consequences
but the functional antecedents
but the functional groups
but the true consequences
but the functional models
but the fiscal consequences
but the unintended consequences
but the functional consequence
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com