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The gene Frost (Fst) was first discovered when Drosophila flies were exposed to cold stress, but the biological function(s) of Fst has so far not been characterized.
Alternative splicing appears widespread in eukaryotes, but the biological function of alternative splicing is still poorly understood.
Furthermore, the enzyme also catalyzes the epimerization of DHNP to 7,8-dihydromonapterin (DHMP) at a significant rate, but the biological function of DHMP is not clear [ 2].
In Dickeya genus, D. zeae Ech586 and D. chrysanthemi Ech1591 were shown to possess an identical T6SS loci consisting of 17 genes [ 43], but the biological function has not yet been determined.
In addition, our previous proteomic study on FLSs derived from the synovial membrane also found that KIAA1199 expression in RA patients was significantly higher than in healthy controls [ 19], but the biological function and mechanism of action of KIAA1199 in RA remain unknown.
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A comparison of the relative frequency of gains and losses at specific loci may provide insight not only into the likelihood that change at a specific locus is of biological significance, but into the biological function of the associated genes as well.
Arabidopsis genome contains 12 HAT genes, but the biological functions of many of them are still unknown.
Since the initial observation, ∼1000 miRNA sequences have been identified in mammals, but the biological functions of a large part remain illusive.
Nucleotide variations in PROSER1 were only observed in FM1, but the biological functions of this proline and serine-rich protein are unknown.
The GRNs were highly dataset specific on the interaction level between individual genes, but showed large similarities on the biological function level represented by subnetworks.
As pointed out by Yanai and his co-worker, the similar gene expression profiles may not imply similar functions [ 17], so the co-expression of bidirectional genes may not be driven by the biological function but by the shared regulatory elements.
More suggestions(15)
but the biological cost
but the biological role
but the biological sense
but the biological relationship
but the renal function
but the biological behavior
but the biological rhythm
but the biological pathway
but the real function
but the biological feasibility
but the biological evidence
but the ultimate function
but the biological mechanism
but the biological nature
but the biological fact
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Justyna Jupowicz-Kozak
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