Two recent systematic reviews of randomized controlled studies of SMBG in people with type 2 diabetes not treated with insulin reported small but significantly greater decreases in HbA1c among patients using SMBG than in controls (110, 111).
An intention-to-treat analysis revealed significant differences between baseline and 6 months in HAM-D and pain scores, QOL, and A1C and systolic blood pressure levels in both groups, with no differences between groups for the first three but a significantly greater decrease with sertraline in A1C and systolic blood pressure levels.
There was no difference in PWC170 at baseline between the two groups, but offspring had significantly greater decrease in PWC170 during follow-up.
BACE1 −/−, but not BACE1 +/−, mice showed a significantly greater decrease in blood glucose during ITTs (insulin tolerance tests) at all of the time points examined.
Significant reductions from baseline in HbA1c in these high-risk patients with type 2 diabetes, inadequately controlled with two or more OADs, were similar in both treatment groups, but patients with exenatide treatment had a significantly greater decrease in weight compared with those treated with insulin glargine, where there were increases in weight, over 26 weeks.
Local cold-pack application was associated with a significantly greater decrease of the pro-inflammatory mediator IL-1β, but had no effect on circulating IL-6 levels.
The authors reported that patients undergoing Ilizarov correction had a significantly greater decrease in pain and increase in function at a mean follow-up of 28 months.
Probably as a result of the greater molar extrusion and greater amount of distalization and molar rotation, we found a significantly greater decrease in the SNB angle for the MGBM compared with the Pendulum group.
High-dose (2 g/kg) mannitol produced a significantly greater decrease in serum sodium than low-dose mannitol (1 g/kg) (− 20.7 vs. − 8.7 mEq/L, respectively) and a greater increase in serum osmolality [6].
This alteration in the amount of mandibular growth during active treatment was associated with a significantly greater increase in the SNB angle (0.7°) and a significantly greater decrease in the ANB angle (−1.1°) that remained stable in the follow-up (T1-T3 change, 0.9°, and −0.6°, respectively).
