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On the opposite, a weak but significant protective effect of caspase-10G was observed in SH-EP.
Our study is consistent with a recent meta-analysis that concluded a small but significant protective effect of MTHFR C677T exists against colorectal cancer risk (overall TT versus CC OR = 0.93; 95% CI, 0.89-0.98) for a worldwide population [ 28].
Smoking (both exsmokers and smokers; OR=0.80 and 0.68, respectively) and frequent contact with noxious substances (OR=0.83) were found to have a mild but significant protective effect on odour recognition/memory (table 2).
The carrier status of the minor alleles of the CGB5 promoter SNPs exhibited a modest but significant protective effect against RM occurrence (P=.021; c5-155: OR = 0.64; 95% CI, 0.44 0.94; and c5-142: OR = 0.66; 95% CI, 0.45 0.94; Table 2).
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The consumption of the folk style vegetarian food showed a significant protective effect (OR=0.67, 95% CI=0.47, 0.94).
As the PHF is a proprietary Ayurvedic formulation having many components with very low concentrations, the mild but significant protective effects observed on inflammation, angiogenesis and cataract can have cumulative and synergestic effects while on repeated topical applications in patients for their obvious therapeutic effect with low or no toxicity as observed in clinical studies.
After adjustment for age, sex, obesity and indication for statin, the association between pre-admission statin use and severe outcome was not statistically significant; point estimates are compatible with a small but clinically significant protective effect of statin use [adjusted OR: 0.72 (95% CI: 0.38 1.33)].
Although not complete, the extent of TNFR1 knockdown that we obtained was sufficient to protect the cells from TNF-induced necroptosis, but had no significant protective effect on brefeldin A cytotoxicity.
Intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine (SP) in infants (SP- IPTi) reduced the incidence of clinical malaria in areas of sub-Saharan Africa with low to moderate SP resistance in sub-Saharan Africa [1] [5] but had no significant protective effect in one area of high SP resistance [6] and one area of low transmission [7].
wild-type and FGFR2S252W had a modest, but not statistically significant, protective effect against apoptosis that was lost with FGFR inhibition (Fig. 5D).
However, in women who had preterm pre-eclampsia in first pregnancy, partner change was strongly protective for recurrence of preterm pre-eclampsia, but there was no significant protective effect of partner change on risk of term pre-eclampsia.
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