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Apoptosis induced by apoptin is p53-independent, but requires activation of caspase 3 [ 7, 8, 37, 51, 52].
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FGF-2-induced endothelial migration in vitro is not dependent on PKC/PLA2 or pertussis-toxin sensitive G-protein pathways but rather requires activation of a phosphoinositol (3 -kinase-like enzyme and/or arachidonic acid release with subsequent liberation of lipoxygenase products.
These data suggest that activity burst behavior requires activation of more SF1+ neurons than does freezing.
Phosphorylation of c-Jun on Ser63 requires activation of PKA, but not EPAC1.
Likewise, high- and low frequency stimulation-induced LTP [ 15,19] but not opioid-withdrawal LTP [ 18] requires activation of CaMKII.
c-Jun protein is activated by a phosphorylation cascade that requires activation of MEK-ERK and JNK.
BMP-mediated cell migration requires activation of the small GTPase Cdc42 and LIMK1 activities.
Sumoylation requires activation of the mature form of SUMO by a heterodimeric activating (E1) protein.
These findings indicate that chromosome decondensation requires activation of the CMG helicase during the initiation of chromosome replication but is independent of ongoing DNA synthesis during elongation.
Cardioprotection by postconditioning requires activation of mitochondrial large-conductance Ca2+-sensitive potassium (mBKCa) channels.
This requires activation of the cognitive and meta-cognitive strategies to be able to comprehend the listening input.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com