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Our hypothesis is not contradicted by the observation of dedifferentiation in cancer tissues, but rather parallels this finding: tissues with a greater dedifferentiated phenotype will express a less specialized transcriptome.
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Similarly, the different series of the different isotopologues of a homologue compound are unlikely superjacent but rather parallel in orientation in the m/z vs. RT plane.
The logo for the band Kiss, which originally had three Jewish members, was made to look just like the insignia of the SS -- not quite a swastika but rather two parallel, jagged s's made to look like lightning.
These results are not compatible with an epistatic genetic relationship expected from a ligand-receptor pair but rather indicate parallel functions for lat-1 and ten-1.
We are starting to understand that ligand-mediated signaling is not a one-directional linear process, but rather a parallel process with different dependent, independent, cross-linking, correlating, and influencing pathways and eventual effects [ 49– 51].
The principal obstacle to any RGC methods is homoplasy, i.e., the same amino acid replacements that occur in different lineages independently and thus do not reflect common ancestry but rather represent parallel, reverse, or convergent changes [ 15].
Current complexity of human physiology cannot be solely explained by expression of 20000 protein-coding genes, comparable to that observed in Drosophila melanogaster and Caenorhabditis elegans, but rather by parallel development of a noncoding genome.
Clones that are generated during late embryogenesis are still present and growing actively several months after, showing that they do not displace each other but rather extend parallel to the growth axis.
In order to reduce the level of homoplasy, that is, the same amino acid replacements in different lineages that do not reflect common ancestry but rather represent parallel, reverse, or convergent changes (Telford and Budd 2003 ), the RGC_CAM method analyzes only those amino acid replacements that require two or three nucleotide substitutions (fig. 2 A ).
About 15 years after delivery, the risk curves were rather parallel, but with a consistent difference in risk according to age at first birth.
The risk curves were rather parallel after about 15 years, but with an overall difference in risk between those with a second birth below and above the age of 25 years.
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