Sentence examples for but rather downstream from inspiring English sources

That the expression of many E.coli LPS-responsive genes remains unaffected by F. tularensis infection suggests that the target is not the TLR4 receptor but rather downstream in the signaling pathway.

However, the differential effect on LPS-responsive gene expression suggests that FT SchuS4 is not targeting the TLR4 molecule directly but rather downstream in the signaling cascade, such as an adaptor protein(s) or transcription factor(s).

DDX3X belongs to the same family of helicases as RIG-I and MDA5 and yet, its mode of action in innate immunity seems to be distinct: unlike RIG-I and MDA5, DDX3X does not exert an effect as a PRR, but is situated rather downstream in the signalling cascade that controls IFN-β production.

These results suggest that rapa may not target the deprotected telomere state induced by inactivation of Cdc13p, but rather the downstream death pathway.

These results thus indicate that BCR/ABL does not interfere with the function of the FA core complex, required for FANCD2 monoubiquitination, but rather with downstream steps in the FA pathway.

Of these, many may be extragenic, since translation may initiate not at the predicted, but rather at downstream sites.

However, BIP levels remain unchanged because TUDCA did not eliminate the accumulation of misfolded proteins, but rather targeted downstream events only.

Therefore the signal emanating from mitochondria and activating AMPK in the endothelium of patients with CAD and T2D is unlikely to be H2O2 itself, but rather a downstream radical with which MitoQ10 reacts.

The fact that the dbf4-NLSΔN221 dbf4-NLSΔN221 strainise to HU inotitotic cellsensitivelse etoal., 2006) suggests tHUt thin allele does not bypass checkpoint activation, but rather acts downstreamitotic parallel to Mecellsd Rad53.

The charge-reversing E650R mutation caused a slight left-shift of the dose response curve of cadmium activation, in contrast to the right-shift observed with the more conservative size-preserving E650Q mutation, further supporting the notion that this residue does not directly coordinate metal ions but rather works downstream of metal ion binding for channel activation.

Although UNC-73 could potentially exert a similar effect in VD growth cones that our assays did not detect, the results reported here are consistent with the idea that UNC-73, UNC-33 and UNC-44 do not affect UNC-5 and UNC-40 accumulation in VD growth cones but rather act downstream to mediate changes in growth cone protrusion.