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These observations suggest that the insensitivity of human normal liver cells to Lexa and CHX combination treatment is not controlled by death receptor 5 (DR5) expression level on the cellular membrane, but rather determined by the expression levels of intracellular pro-apoptotic proteins, including Bax, Bak, and Bid.

In the CBT, visit schedule (at least once a week) was not dictated by the trial protocol but rather determined by the visiting nurse.

The necessary combination of voxel- and cluster-level thresholds is not assumed from theory but rather determined by direct permutation for each data set.

However, if the glycocalyceal volume is not fixed, but rather determined by osmotic water movements, then there must also be an osmotic equilibrium at steady state.

Randomised controlled trials (RCTs) and quasi-RCTs (the group allocation was not purely random but rather determined by a factor such as a birth date, a hospital record number or an alternation) will be included.

In contrast to other studies that used a single question asking patients to rate their disease severity as mild, moderate, or severe, this analysis did not rely on a direct question, but rather determined pDPN severity based on two questions.

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In an interview more than a decade ago he noted: "The key to investing is not assessing how much an industry is going to affect society, or how much it will grow, but rather determining the competitive advantage of any given company and, above all, the durability of that advantage.

Accordingly, scholars contend that while genetic factors are important, they do not operate in isolation, but rather determine resilience/vulnerability jointly with a number of other variables, including environmental characteristics [ 53].

Indeed, it has been reported before that the caspase-like activity has only a minor contribution of bulk protein degradation by the proteasome but rather determines degradation rates of specific substrates and the composition of the degradation products [ 32, 33].

Furthermore, we reveal that in this context NonO and SFPQ are not classical transcriptional regulators of RP gene expression, but rather determine the positioning of the transcriptional machinery on RP gene promoters.

This test does not directly compare the outcomes of the intensity- and ratio-based analysis, but rather determines which of the two analyses is most suitable to analyze the data.

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