Therefore, the fact that the biochemical assay detection is not specific to GSH or GSSG, but rather detects total thiols and disulfides in the supernatant fraction of tissue homogenates (for which GSH and GSSG are normally the major components) should be kept in mind when interpreting these results.
As noted above, the M-statistic does not locate hot spots, but rather detects a difference between the two populations under comparison.
Unfortunately, this primer did not straddle the inversion breakpoint but rather detected the existence of a 2-kb insertion sequence (data not shown) which correlated with the type of Z chromosomes.
Likewise, in another study [ 11], the authors did not report a correlation between the occurrence of this motif and a particular class of genes, but rather detected the GTGT motif to be specifically enriched in regions with a particular chromatin 'anatomy', namely, those regions enriched for PRC1 proteins and with H3K4Me3 at the transcription start site.
Unbiased metagenomic NGS is a powerful approach for diagnosis of infectious disease because it does not rely on the use of targeted primers and probes, but rather, detects any and all pathogens on the basis of uniquely identifying sequence information [ 44].
The polygraph test depends on this: "Lie Detectors" don't actually detect lies, but rather they detect the subconscious stress and fear that lying causes.
Since our goal was not to find homologous sequences but rather to detect the most probable and specific sequence in the nucleotide database, megablast was preferred over other optional tools.
The technologies used to analyze SNPs are not intended to discover new point mutations, but rather to detect ancient genotypes carried by thousands of people (for example, apolipoprotein E4, Online Inheritance in Man (OMIM) ID 104310) and sickle cell mutation (OMIM-603903); they also can detect recurrent new mutations (for example, achondroplasia, OMIM-100800).
Hyperacetylation of target proteins was rather detected in basically all patients treated with an HDACi, but at least a dose- and time-dependent increase in acetylation levels could be observed (Chung et al. 2006).
A concentration-dependent increase (P < 0.05) in cell activity was rather detected in most of our experimental conditions.
