Rather a time-dependent fluctuation in mycotoxin concentrations exists in vivo, whereas in vitro cells are exposed continuously at constant concentrations.
In many diseases, however, it has not yet been possible to detect a specific change of a certain metabolite, but rather a complex time-dependent modulation of several compounds.
Even if the culture medium was renewed at day 5, a similar level of TNF-α was found 24 h later (at day 6), indicating an increase in TNF-α secretion after irradiation rather than a time-dependent accumulation of this cytokine.
Most groups consider it in terms of disease severity, treatment-related complications, and disability rather than as a time-dependent process.
Rather, recurrent networks process a time-dependent signal one frame at a time, using feedback connections that create a memory of previous inputs.
Meanwhile, melatonin supplementation stimulated progesterone production, but inhibited estradiol biosynthesis, in a time-dependent manner.
Blastocystis ST-7, but not ST-4, induced a time-dependent drop in Caco-2 TER.
FAF1 mRNA was upregulated following CD40 ligation in CD40-positive cells but not in CD40-negative cells in a time-dependent manner, confirming that FAF1 upregulation was due to increased transcription rather than protein stabilisation.
This score results in a time-dependent rank with a rather complex behaviour, as we will explain below.
