Sentence examples for but one study used from inspiring English sources
All but one study used a before-after design without any element of randomization.
All but one study used a cluster allocation design, randomising all included general practices to either intervention or control group.
All but one study used suggestions and/or images which were directly addressed to the pain experience.
In at least two animal studies, researchers did not observe increased body weight after in utero exposure to PFOA (Butenhoff et al. 2004; Macon et al. 2011), but one study used higher doses (≥ 1mg/kg) (Butenhoff et al. 2004) and the other followed animals only until 12 weeks of age (Macon et al. 2011).
If this is the case, it is unlikely to have affected the summary estimates obtained for the 3-5 ng/L cut-off value, as in this meta-analysis all but one study used a standard assay as the reference test.
GLP-1 and its analogs have been less well studied in type 1 diabetic patients, but one study using high-dose exenatide in subjects with type 1 diabetes shows reduced body weight, lower insulin requirements, and reduced blood glucose variability without significant changes in C-peptide secretion or A1C (28).
Allocation concealment was clearly adequate in four studies but only one study used double blinding.
But, only one study used insulin glulisine (37 studies used insulin lispro, 10 used insulin aspart, one used insulin lispro and insulin aspart).
However the problem of confounding factors such as smoking, maternal age, parity and vascular complications of diabetes, was noted by most of the studies but only one study used the appropriate statistical test to quantify the effect of the PCC apart from the confounders [ 10].
Finally, a systematic review of the effectiveness of critical appraisal skills in the training of clinicians showed an overall improvement of 68% in assessed outcomes following intervention, but only one study used a randomized controlled design and the methodological quality of the studies included was poor [ 13].
One study used dialysis on sample extracts [26], which likely distorted the relative peak areas.
