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Estimated creatinine clearance formulas (sMDRD, CKD-EPI, Cockroft and Gault) must not be used because they were developed for stable patients with chronic renal insufficiency (CRI), but not validated in critically ill patients [2].
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Thirdly, five more prediction models have been developed but were not validated in this study.
The interventions were designed using participatory design with a limited number of patients but were not validated in terms of how the users perceived the information and if they correctly understood it and the implications.
A moderate association was noted in a well characterized, admixed PsA cohort from Toronto, but this was not validated in a homogenous Caucasian cohort from Newfoundland.
There is an instrument to assess quality of life in drug users, but it was not validated in Brazil yet (Drug User Quality of Life Scale: DUQOL) [ 24].
In the past, we already applied the MALDI-QqQ-MS/MS for the analysis of LPV and RTV in plasma samples, but this method was not validated in compliance with the FDA regulations [ 19].
Additionally, five genes that were consistently differentially expressed in both TNBC and HGS-OvCa, but their regulations were not validated in either TNBC or HGS-OvCa (FOXA1, CDC25C, CCNE1, CCNE2, MCM4).
Of these, 24 were shown by capillary sequencing of PCR products to contain the expected polymorphism (and some contained additional SNPs), but polymorphisms could were not validated in the remaining 11, which were assumed to be monomorphic.
The European Organization for Research and Treatment of Cancer EORTCC) risk scores are not validated in an independent patient population.
The supporting information is not validated in any way.
This arrangement as control variable was not validated in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com