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SPP86 inhibited TPC1 cell proliferation more effectively than PF573228 (49% proliferation vs. 77%) but no additive effect was observed following co-exposure to both drugs.

The highest amount of functional TF in plasma was noted at shear rates between 1000 2000 s−1 but no additive effect was demonstrated when agonists were combined.

However, when OVA-sensitized animals were exposed to CAPs, stress axis activity remained elevated but no additive effect was observed.

Cef/met alone reduces the mortality rate in rats with peritoneal contamination and infection, but no additive effect was obtained by combining it with G-CSF.

By contrast ICAM-1 was upregulated in all the conditions tested when compared to controls but no additive effect was observed.

Lambs gavaged with 0.023 g OVA for 9 days (Group C) generated significant anti-OVA IgA titres in lung compared to negative control lambs but no additive effect was observed compared to parenteral control lambs.

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PE stress induced activation of Akt and NFAT3 in LacZ-treated NCM's to levels similar to those observed with myostatin inhibition but had no additive effect in dnMSTAT-treated cells (Fig. 7A, B).

Additionally, in an intermediate chronic stage, such as cybrids, cells may eventually succumb to biochemical processes typically associated with apoptosis when autophagy is inhibited by 3-MA, in accordance with NT2 cells, but has no additive effect on sPD cybrids.

After 9 months the reduction remained in both groups but no additive effects were encountered in any of the groups.

In beef cattle, presynchronisation with progesterone supplementation has been studied, but no additive effects were detected [ 27].

Like other proinflammatory cytokines, MIF stimulates the expression of RANKL mRNA and protein in RA synovial fibroblasts, but there was no additive effect with other proinflammatory cytokines such as TNF-α and IL-1β.

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