The precise mechanisms behind this pain augmentation are not known as yet, but most likely encompasses multiple changes in the central nervous system.
Mikhail Yangel was appointed head designer, but his job was complicated by multiple changes in the role of the aircraft from escort fighter to interceptor, dive bomber, and eventually reconnaissance.
Most BRCA1 or BRCA2 gene aberrations are small mutations involving a single or multiple changes in nucleotide sequence, but large genomic rearrangements (LGRs) have also been reported in patients who are negative for BRCA1 or BRCA2 sequence variations.
This raises the question of whether the phenotypic differences between wdw vV, wdw lV and wdw gV are due to multiple changes in a single gene, or at different but tightly linked genes.
Hypoxia induced multiple changes in transcripts related to these processes in WT, but only moderate changes in AtHb1 plants.
Instead they became the latest top-flight side to pay the penalty for making multiple changes in the competition and produced a lacklustre display.
A person familiar with security on the ferries said that other measures now in place include having police officers in plain clothes on some crossings, special attention to customers who make multiple changes in reservations and more truck searches.
There have been multiple changes in front of the camera: Hewer is just the current holder of a chairing baton that passed from the late Whitely to the rather diffident Des Lynam, then subsequently to Des O'Connor and Jeff Stelling.
Among the indicators: multiple changes in title ownership, or flipping; the transfer of titles at below-market prices; and the sale of properties at prices beneath the minimum amount required for tax filings.
Arizona, for example, made multiple changes in its child support guidelines last October.
